Members

Khaled ALASAAD ALWEKYAN

Benjamin LEVY

Amad KAYTOUE

Amine HALIMI

Contact :
khaledwakyan123@gmail.com

3D models of cutaneous sensory and perception innervation

Latest research shows an important increase of dermal diseases, especially atopic dermatitis, which has affected these last years more than a third of all children and more than 10% of adults. Verneuil disease, another dermal disease affects more than 1% of the population, enduring painful symptoms and  inflammation.

Research models have been proposed by research laboratories, using skin grafts based on stem cells. The most important missing part in these models is the innervation of the different components of the skin, and the sebaceous glands which are very difficult to reproduce  in vitro.

The primary purpose of our innovative idea consists in  developing cutaneous sensory and perception innervation which play a major role in skin physiopathology inflammation with sebaceous glands based on stem cells matrix  and by using biomaterials to maintain the efficiency and durability of the grafts by finding the perfect consistency and biocompatibility, which will allow us to test other substances, caracterise and propose treatments for diseases such as those  mentioned before, as well as contribute to rapid wound closure.

.Poster / Images

Diagram Organo-Skin composition (longitudinal section view from above)

Acknowledgments

Author: Khaled ALASAAD ALWEKYAN

I am Khaled ALASAAD ALWEKYAN, I validated the M1 biomaterials for health at the University of Strasbourg